2 edition of Standardization of antipneumococcus horse sera and concentrates found in the catalog.
Standardization of antipneumococcus horse sera and concentrates
Lloyd Derr Felton
|Statement||[by] Lloyd D. Felton and H.J. Stahl. From the Department of preventive medicine and hygiene, Harvard medical school, Boston.|
|Series||U.S. [National institute of health] National institute of health bulletin ;, no. 169, National Institute of Health bulletin ;, no. 169.|
|Contributions||Stahl, Helen J.|
|LC Classifications||RA421 .U4 no. 169|
|The Physical Object|
|Pagination||iii, 58 p. ;|
|Number of Pages||58|
|LC Control Number||37026197|
Publisher Summary. This chapter discusses genetics of blood groups. The inkling of complexity of a blood group system usually comes from the investigation of a rare recessive phenotype affecting the system, which results in the absence of expected antigens—for example, the Bombay phenotype in the ABO system, p and P k in the P system, and KL in the Kell system. Reaching the large house near the Horse Guards’ barracks, in which Anatole lived, Pierre entered the lighted porch, ascended the stairs, and went in at the open door. There was no one in the anteroom; empty bottles, cloaks, and overshoes were lying about; there was a smell of alcohol, and sounds of voices and shouting in the distance.
Access quality crowd-sourced study materials tagged to courses at universities all over the world and get homework help from our tutors when you need it. The sera are pooled samples collected from healthy adult goats, horses, chickens, swine, rabbits, cats, and dogs. Each one is heat-treated and centrifuged to remove precipitates and then filtered. The sera are tested with appropriate antibody to check for possible cross-reactivity.
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Production and Standardization of Antipneumococcus Serum, an article from American Journal of Public Health, Vol 31 Issue 2 LOGIN TO YOUR ACCOUNT EmailCited by: 1.
The ratio precipitin/protective antibody is given for several fresh antipneumococcus horse sera (Type II). The application of the precipitin test here dealt with and that of similar ones, based on the conception of a parallelism between precipitin and protective antibody, is limited to unrefined horse by: 1.
Antipneumococcus Sera I, II, and III agglutinated all the strains in fairly high dilution ( to or higher), while normal horse serum caused no agglutination. Antipneumococcus Sera I, II, and III stimulated active phagocytosis of all the strains, while no phagocytosis occurred in control preparations with normal horse by: 7.
a study of pneumococci reacting with antipneumococcus sera of types i, ii, and iii, with an observation of a mutation of one of the strains ON THE PRESENCE IN ANTIPNEUMOCOCCUS SERUM OF TYPE-SPECIFIC PROTECTIVE ANTIBODY NOT NEUTRALIZED BY Cited by: 8. Methods for the titration of antipneumococcus sera have been evolved, and some of the therapeutic preparations used hitherto have been labelled as containing a certain number of [quot] units.[quot] Until one standard serum is available, however, in terms of which all others may be assayed, such labelling can have little value, and may indeed be Cited by: 4.
Types I and II sera obtained in our experiments with culture sediment and whole culture did not vary markedly for a given type and corresponded closely in their protective titer with samples of sera received from The Rockefeller Institute Hospital.
It is therefore evident that the following minimum standard of cc. of serum to protect mice. The problem of passive sensitization against the soluble specific substance or the cellular carbohydrate with antipneumococcus horse serum was considered from the point of view that this serum either lacked a factor necessary for the sensitization of guineapigs or contained an inhibiting substance.
Type-I antipneumococcus serum failed to sensitize even after the addition of normal rabbit serum. To this end, a dry stable standard for antipneumococcus serum, type I., was prepared in this institute (Hartley et al., ) and assayed, as accurately as the methods at present available allow.
in terms of the type I. component of the liquid serum F. ; it was established that mg. of the dry stable standard for antipneumococcus serum. The results from seven such sera show that this therapeutic value does not parallel the mouse-protective value.
It is suggested that the rabbit technic may prove useful for the routine comparison and standardization of antipneumococcus sera since it represents a simple method for determining that property for which the serum is to be utilized.
some effects of formaldehyde on horse antipneumococcus serum and diphtheria antitoxin, and their significance for the theory of antigen-antibody aggregation Harry Eagle From the Syphilis Division, Department of Medicine, Johns Hopkins Medical School, Baltimore, and the United States Public Health Service, Washington, D.
specific precipitation and mouse protection in type i antipneumococcus sera michael heidelberger. Books at Amazon. The Books homepage helps you explore Earth's Biggest Bookstore without ever leaving the comfort of your couch. Here you'll find current best sellers in books, new releases in books, deals in books, Kindle eBooks, Audible audiobooks, and so much more.
The addition of a water-clear extract of pneumococci to homologous antiserum produces a voluminous precipitate which carries down with it the agglutinins and practically the totality of the protective bodies against pneumococcus infection in animals.
doses of standard culture ranged from c.c. to and even c.c. Antipneumococcus serums which were produced by different laboratories were obtained, and the protective potency of all of them was tested. The results of all of these tests are recorded in Table 1.
The laboratories are designated by letters, and the letters which have. Production and Standardization of Antipneumococcus Serum * Harold W. Lyall * Read before the Laboratory Section of the American Public Health Association at the Sixty-ninth Annual Meeting in Detroit, Mich., Octo CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): In preceding papers (1, 2) it has been reported that Type I antipneumococcus horse serum, in amounts exceeding a characteristic optimum, fails to protect mice against infection with the homologous type pneumococci.
This effect was shown to be associated with a marked inhibition of the phagocytic mechanism in the. The sera employed comprised ordinary antipneumococcal horse sera, heterophile antiserum prepared by inoculating rabbits with sheep's red cells, a polyvalent antipneumococcal serum prepared in the rabbit and containing a high titre of heterophile antibody and a low titre of type-specific antibodies, and mixtures mixtures Subject Category.
Quantitative Immunochemical Aspects of Some Allergie Reactions* ELVIN A. KABAT, Ph.D. New York, New York WHILE the concept of allergie reac- tions as caused by the combination of antigen with antibody in the tissues is unequivocally established (for earlier studies,1'5) knowledge of the severity of the allergic response as a function of the amounts of antigen and antibody involved is quite.
The observations of HARTLEY have shown that the lipoid components of antisera are intimately associated with the occurrence of specific precipitation in vitro.
The authors record an interesting series of experiments dealing with this problem in particular relation to the interaction of the Type I pneumococcus with its homologous antibody. Type I antipneumococcal horse serum was found to be.
Immediate " serum reactions are those occurring within two hours of the administration of serum. They occurred in ( per cent.) of 2, patients receiving Types I, II, V, VII or VIII antipneumococcal serum. Inthe reaction was simple-either thermal, " anaphylactic, " circulatory or miscellaneous; in the remaining it was a mixture of two or more of these components, the thermal.
A dry, stable, standard serum (Type I.), of which a definite weight represents one British provisional unit, has been prepared in the department of biological standards of the National Institute for Medical Research, London, where it is maintained under optimum conditions of storage and is available for the titration of Type I.
sera.“THE SPECIFIC ANTIBODIES OF ANTI-PNEUMOCOCCUS SERA”, American Journal of Public Hea no. 9 (September 1, ): pp. DOI: /AJPH Recommend this Journal to .Henry Welch, Earle K. Borman, and Friend Lee Mickle “Preparation and Analysis of Diagnostic Antipneumococcus Serum”, American Journal of Public Hea no.
1 (January 1, ): pp. DOI: /AJPH